Melanopsin gene polymorphism and volumetric change in the left hippocampal dentate gyrus following light therapy in mood disorders: An exploratory study
Hirofumi Hirakawa, Masaaki Muronaga, Toshihiko Izumi, Kentaro Kohno · 2026
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Description
A peer-reviewed research article from Europe PMC (2026). IntroductionBright light therapy (BLT) is an effective treatment for mood disorders. We previously reported that four weeks of bright light (BL) exposure in patients with mood disorders led to increased volume of the left dentate gyrus (DG). We propose a novel hypothesis that the extent of light-induced volumetric increase in the left DG may be influenced by individual genetic variation in the OPN4 gene, especially rs1079610.
Catalog record
| CREATOR | Hirofumi Hirakawa, Masaaki Muronaga, Toshihiko Izumi, Kentaro Kohno |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |