Swelling-induced calcium signaling in wild-type and Mlc1-null astrocytes: paradoxical effects of pharmacological TRPV4 and Piezo1 inhibition
Quinty Bisseling, Vera Kuhnke, Maria S. Brignone, Elena Ambrosini, Huibert D. Mansvelder, Marjo S. van der Knaap, Rogier Min · 2026
Read Swelling-induced calcium signaling in wild-type and Mlc1-null astrocytes: paradoxical effects of pharmacological TRPV4 and Piezo1 inhibition by Quinty Bisseling, Vera Kuhnke, Maria S. Brignone, Elena Ambrosini, Huibert D. Mansvelder, Marjo S. van der Knaap, Rogier Min (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13518189.txt.
Description
IntroductionAstrocytes play a crucial role in brain ion and water homeostasis and continuously adapt their volume in response to osmotic challenges. This process is disturbed in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts (MLC). Intracellular calcium signaling in response to cell swelling has been implicated in astrocytic volume regulation.
Catalog record
| CREATOR | Quinty Bisseling, Vera Kuhnke, Maria S. Brignone, Elena Ambrosini, Huibert D. Mansvelder, Marjo S. van der Knaap, Rogier Min |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |