Rare missense variants in NECTIN1 alter local protein structure and may contribute to non-syndromic cleft lip with or without palate
Ana Luiza Meneguci Moreira Franco, Deborah Antunes, Ana Carolina Proença da Fonseca, Ana Clara Rodrigues Moreira Gomes, Ana Carolina Ramos Guimarães, Ieda Maria Orioli, Flavia Martinez de Carvalho · 2026
Read Rare missense variants in NECTIN1 alter local protein structure and may contribute to non-syndromic cleft lip with or without palate by Ana Luiza Meneguci Moreira Franco, Deborah Antunes, Ana Carolina Proença da Fonseca, Ana Clara Rodrigues Moreira Gomes, Ana Carolina Ramos Guimarães, Ieda Maria Orioli, Flavia Martinez de Carvalho (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13518071.txt.
Description
IntroductionOrofacial cleft is a congenital anomaly influenced by genetic and environmental factors. NECTIN1 encodes an adhesion protein critical for the adherens junctions and has been associated with orofacial clefts. This study aimed to investigate the contribution of NECTIN1 to the etiology of NSCL/P in a population from Patagonia, Argentina, a region with a high prevalence of orofacial clefts.
Catalog record
| CREATOR | Ana Luiza Meneguci Moreira Franco, Deborah Antunes, Ana Carolina Proença da Fonseca, Ana Clara Rodrigues Moreira Gomes, Ana Carolina Ramos Guimarães, Ieda Maria Orioli, Flavia Martinez de Carvalho |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |