Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter · 2026
Read Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection by Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13518061.txt.
Description
Maria Zabala-Rodriguez and co-authors study how the typhoid bacterium tones down its own toxins in this 2026 paper. The bacterium infects only humans and causes typhoid fever. Long gallbladder infection helps it spread. Its main toxin helps the germ slip into the gut quietly at first. The toxin has a binding part and two working parts that harm cells. It travels inside cells to a staging area before its parts exit to act.
The paper asks why the toxin's full power seems held back in practice. Limiting that power may let the germ settle in for a long stay instead of killing its host cells fast. The authors trace the toxin's path and effects in cell systems. Their account links toxin control to the germ's stealth strategy. The work is a lab study of the infection process.
Catalog record
| CREATOR | Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |