Cerebral Kounis Syndrome—A Rare Case Report of Cerebral Vasospasm Following Anaphylaxis
Mohd Helmie Ismail, Sadesvaran Muniandy, Muhammad Shafiq Azmi · 2026
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Description
Ismail and colleagues reported a 2026 case of cerebral Kounis syndrome, in which a severe allergic reaction triggered spasm of a brain artery and produced a stroke mimic. The patient was a previously healthy 45-year-old man working outdoors who developed full-body itching and rash, near-fainting, breathlessness, palpitations. Abdominal pain, together with sudden weakness of his right side and slurred speech.
Ismail describes how prompt intramuscular epinephrine and other anti-inflammatory treatment brought rapid, complete recovery in the emergency department, and brain imaging and other studies showed no lasting damage. Kounis syndrome is named for allergy-driven spasm of the heart's arteries, which is often mistaken for a heart attack; this case extends it to the cerebral circulation. The authors stress that recognizing allergy as a stroke cause matters, because epinephrine given early is the crucial treatment and delay risks misdirected care.
Catalog record
| CREATOR | Mohd Helmie Ismail, Sadesvaran Muniandy, Muhammad Shafiq Azmi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |