Eicosapentaenoic Acid (EPA) Alleviates Oxidative Stress and Inflammatory Responses in Canine Ileal Epithelial Cells
Xiaoyue Yuan, Xizhu Zhu, Chuyang Zhu, Yunhan Wang, Chenhui Li, Minghua Yu, Fanfan Meng, Ping Hu, Haoyu Liu, Qu Chen, Demin Cai · 2026
Read Eicosapentaenoic Acid (EPA) Alleviates Oxidative Stress and Inflammatory Responses in Canine Ileal Epithelial Cells by Xiaoyue Yuan, Xizhu Zhu, Chuyang Zhu, Yunhan Wang, Chenhui Li, Minghua Yu, Fanfan Meng, Ping Hu, Haoyu Liu, Qu Chen, Demin Cai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13517765.txt.
Description
Yuan and colleagues report a 2026 cell study of omega-3 fats and gut cell protection in dogs. Two fats, EPA and DHA, were compared on dog intestinal cells injured with hydrogen peroxide, a standard oxidative stress test. The team measured cell survival, antioxidant enzymes, inflammation signals, aging markers, and the proteins that seal the gut barrier.
Across all tested doses, DHA failed to relieve the injury, while EPA protected the cells clearly. EPA raised antioxidant enzyme activity, calmed inflammatory signaling, and steadied the cell's chromosome-cap structures, slowing stress-driven aging. It also restored tight junction proteins, the seals between gut cells whose loss makes the gut leaky. The split between two similar fats is the surprise: for dog gut health, EPA looks like the active partner, a lead for pet foods aimed at intestinal protection.
Catalog record
| CREATOR | Xiaoyue Yuan, Xizhu Zhu, Chuyang Zhu, Yunhan Wang, Chenhui Li, Minghua Yu, Fanfan Meng, Ping Hu, Haoyu Liu, Qu Chen, Demin Cai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |