Fascial Remodeling After Botulinum Toxin Injection in Post-Stroke Spasticity: A Retrospective Ultrasonographic Study
Betül Aydın, Münire Nazlı Höbek Başer, İpek Midi, Naime Evrim Karadağ Saygı, Özge Keniş Coşkun · 2026
Read Fascial Remodeling After Botulinum Toxin Injection in Post-Stroke Spasticity: A Retrospective Ultrasonographic Study by Betül Aydın, Münire Nazlı Höbek Başer, İpek Midi, Naime Evrim Karadağ Saygı, Özge Keniş Coşkun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13517405.txt.
Description
Aydın and co-authors ask whether botulinum toxin reshapes the tissue around spastic muscles, not just the nerves. Their 2026 retrospective ultrasound study follows 37 stroke patients treated with botulinum toxin type A for focal spasticity. Fascial thickness, the connective tissue wrapping the muscles, was measured before treatment, at three weeks, and at three months in the injected regions, alongside standard clinical scores.
Fascial thickness fell significantly across all evaluated regions after injection. Most sites thinned by week three and stayed thinner at month three, while three deeper layers kept thinning through the full period. Clinical measures moved in parallel: spasticity scores and upper-limb motor scores improved significantly, though recovery staging did not change. The authors suggest the toxin's benefit partly reflects fascial remodelling, a structural effect beyond nerve blocking, and propose ultrasound fascial measurement as a monitoring biomarker.
Catalog record
| CREATOR | Betül Aydın, Münire Nazlı Höbek Başer, İpek Midi, Naime Evrim Karadağ Saygı, Özge Keniş Coşkun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |