Effects of Parity and the Administration of Caffeine Plus PGF2α on Hormonal and Behavioral Changes During Parturition in Gilts and Sows

Adrián Alejandro Corrales-Hernández, Patricia Roldán-Santiago, Héctor Orozco-Gregorio, Luis A. de la Cruz-Cruz, Ofelia Limón-Morales, Juan Manuel Vázquez García, Herlinda Bonilla-Jaime · 2026

Read Effects of Parity and the Administration of Caffeine Plus PGF2α on Hormonal and Behavioral Changes During Parturition in Gilts and Sows by Adrián Alejandro Corrales-Hernández, Patricia Roldán-Santiago, Héctor Orozco-Gregorio, Luis A. de la Cruz-Cruz, Ofelia Limón-Morales, Juan Manuel Vázquez García, Herlinda Bonilla-Jaime (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13517318.txt.

Description

Corrales-Hernández and colleagues studied how caffeine combined with a birth-inducing hormone affects sows during farrowing, comparing first-time mothers with experienced ones in a 2026 animal study. Pig research usually centers on piglets, leaving the sow's own response understudied, even though intravulvar caffeine is authorized in Europe. The team measured hormones, behavior, and delivery performance under different induction protocols.

Corrales-Hernández found that a split-dose hormone protocol plus caffeine clearly shortened total farrowing time and the intervals between piglets in both parity groups, increased piglets born alive. Reduced perinatal deaths, especially in experienced sows. Treated sows also changed posture less often, a sign of discomfort, and rested more in favorable lying positions. Stress and reproductive hormone patterns during birth depended strongly on whether the sow had given birth before, showing the maternal response is parity-driven and the combination a useful welfare tool.

Catalog record

CREATORAdrián Alejandro Corrales-Hernández, Patricia Roldán-Santiago, Héctor Orozco-Gregorio, Luis A. de la Cruz-Cruz, Ofelia Limón-Morales, Juan Manuel Vázquez García, Herlinda Bonilla-Jaime
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13517318

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