An Integrated Multi-Biomarker Perspective on Acute Exercise: Differential Orexin, Alpha-Amylase, and Cortisol Responses Across Modalities

Fiorenzo Moscatelli, Vincenzo Monda, Marco La Marra, Antonietta Messina, Antonietta Monda, Maria Casillo, Nicola Mancini, Girolamo Di Maio, Gabriella Marsala, Giovanni Messina, Rita Polito · 2026

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Description

A peer-reviewed research article from Europe PMC (2026). Purpose: Acute exercise elicits coordinated neuroendocrine and autonomic responses that are strongly influenced by exercise modality and intensity. While cortisol and salivary alpha-amylase are widely used as peripheral indicators of hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system activation, respectively, salivary orexin remains an exploratory biomarker whose relationship with central orexinergic activity is not yet fully established, particularly in response to different exercise conditions.

Catalog record

CREATORFiorenzo Moscatelli, Vincenzo Monda, Marco La Marra, Antonietta Messina, Antonietta Monda, Maria Casillo, Nicola Mancini, Girolamo Di Maio, Gabriella Marsala, Giovanni Messina, Rita Polito
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE55 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13517111

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