Quality by Design and Process Analytical Technology for On-Demand Drug Manufacturing Through 3D Printing
Imola-Rebeka Turac, Tibor Casian, Sonia Iurian, Alina Porfire, Rareș Iovanov, Daniela Elena Popa, Ioan Tomuță · 2026
Read Quality by Design and Process Analytical Technology for On-Demand Drug Manufacturing Through 3D Printing by Imola-Rebeka Turac, Tibor Casian, Sonia Iurian, Alina Porfire, Rareș Iovanov, Daniela Elena Popa, Ioan Tomuță (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13516036.txt.
Description
Imola-Rebeka Turac and colleagues review how quality-by-design thinking and live process checks could make 3D-printed medicines safe to produce on demand. Printed doses can be tailored to each patient at the care site, but ready quality checks are missing.
Light-based tools, near-infrared and Raman scans, can check printed tablets without destroying them, the review finds. So far these tools mostly check finished products, not the printing process live as a full quality loop needs. Most scan models also work for just one recipe, printer, and drug, with little proof they transfer elsewhere. Turac notes regulators are drafting point-of-care rules, but standard quality demands remain the main barrier to routine use.
Catalog record
| CREATOR | Imola-Rebeka Turac, Tibor Casian, Sonia Iurian, Alina Porfire, Rareș Iovanov, Daniela Elena Popa, Ioan Tomuță |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 131 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |