Agreement and Diagnostic Performance of Urinary HPV Testing Versus Clinician-Collected Cervico-Vaginal Sampling: A Prospective Cross-Sectional Study in a Romanian Cohort

Ionel-Daniel Nati, Mihaela Oancea, Carmen Mihaela Mihu, Dan Mihu, Razvan Ciortea, Cristian Iuhas, Carmen Bucuri, Maria Patricia Roman, Cristina Mihaela Ormindean, Viorela Suciu, Razvan Chereches, Andrei Mihai Malutan · 2026

Read Agreement and Diagnostic Performance of Urinary HPV Testing Versus Clinician-Collected Cervico-Vaginal Sampling: A Prospective Cross-Sectional Study in a Romanian Cohort by Ionel-Daniel Nati, Mihaela Oancea, Carmen Mihaela Mihu, Dan Mihu, Razvan Ciortea, Cristian Iuhas, Carmen Bucuri, Maria Patricia Roman, Cristina Mihaela Ormindean, Viorela Suciu, Razvan Chereches, Andrei Mihai Malutan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13515778.txt.

Description

Ionel-Daniel Nati leads a twelve-author team testing urine-based HPV screening in Romania in a 2026 prospective study. Fewer than twenty percent of Romanian women take up cervical screening, and the invasive swab is a named barrier. The team collected paired samples from 230 women aged twenty-five to seventy at three clinics. Each woman gave a clinician-taken cervico-vaginal sample and a first-void urine sample, tested for fourteen high-risk HPV types, with biopsy as the referee.

The two tests agreed substantially, best of all for HPV16 and HPV18 taken singly. For serious cell changes confirmed by biopsy, urine testing caught about eighty-six percent of cases, close to the swab's ninety-two percent, and a negative urine result was nearly as reassuring. Urine positivity climbed steadily with lesion severity.

Catalog record

CREATORIonel-Daniel Nati, Mihaela Oancea, Carmen Mihaela Mihu, Dan Mihu, Razvan Ciortea, Cristian Iuhas, Carmen Bucuri, Maria Patricia Roman, Cristina Mihaela Ormindean, Viorela Suciu, Razvan Chereches, Andrei Mihai Malutan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52451
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13515778

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