Safety of Fecal Microbiota Transplantation in Children: A Single-Center Experience

Dominykas Varnas, Vaidotas Urbonas · 2026

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Description

Dominykas Varnas and Vaidotas Urbonas review the short-term safety of fecal microbiota transplantation in children at one Lithuanian hospital, in 2026 work. The treatment moves gut microbes from a healthy donor into a patient's bowel and is proven for repeated C. difficile infection, with use growing for other gut and mind-related conditions. Records covered 73 children who received 108 transplants by colon scope between 2017 and 2025, using material from three screened child donors.

About one procedure in ten brought a side effect within three days, all of them mild or moderate, with none rated serious. Loose stools were the most common effect, followed by vomiting. Rates differed by reason for treatment, with the lowest seen in procedures done for autism. The authors say scope-delivered transplantation looks safe in the short term for children, while noting that the underlying illness itself may shape risk and must guide future study design.

Catalog record

CREATORDominykas Varnas, Vaidotas Urbonas
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13511677

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