Methodological Evolution of Diffusion MRI in Chronic Pain: A Narrative Review

Hairui Li, Yuqin Wang, Mingtao Li, Hongan Yang, Zhiqiang Qiu, Xiaoxue Xu · 2026

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Description

Hairui Li and co-authors review, in a 2026 paper, how diffusion MRI methods for studying chronic pain have changed over time. Chronic pain is common and varied, and its workings are still not fully understood. No proven body marker exists to sort patients, explain the pain, or judge treatment, which holds the field back.

Diffusion MRI tracks how water moves in tissue, without cutting or dyes. From that motion, it infers the fine structure and wiring of nerves and brain. The review follows the method from its tensor form to newer multi shell scans. Those add richer models of tiny fibers and their spread, plus links to other scan types. The authors searched two major databases for pain studies through late 2025. Their aim is a method map for researchers choosing tools.

Catalog record

CREATORHairui Li, Yuqin Wang, Mingtao Li, Hongan Yang, Zhiqiang Qiu, Xiaoxue Xu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE70 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13510267

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