Glycosylated Delphinidins, Natural Antioxidants, Functionally Modulate the COX-2/PGE2 Axis and Downregulate MDR1 in Glioblastoma Cells
Constanza Cuevas, Yessica Nahuelpan, Darling Haro, Pamela Silva, Vicente Villagran, María A. Gleisner, Flavio Salazar-Onfray, Juan P. Muñoz, Christian Pávez, Noemi Garcia-Romero, Angel Ayuso-Sacido, Rody San Martin, Diego Carrillo-Beltrán, Claudia Quezada-Monrás · 2026
Read Glycosylated Delphinidins, Natural Antioxidants, Functionally Modulate the COX-2/PGE2 Axis and Downregulate MDR1 in Glioblastoma Cells by Constanza Cuevas, Yessica Nahuelpan, Darling Haro, Pamela Silva, Vicente Villagran, María A. Gleisner, Flavio Salazar-Onfray, Juan P. Muñoz, Christian Pávez, Noemi Garcia-Romero, Angel Ayuso-Sacido, Rody San Martin, Diego Carrillo-Beltrán, Claudia Quezada-Monrás (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13510136.txt.
Description
Constanza Cuevas and co-authors test a berry pigment against drug resistance in a hard brain cancer. Their paper from 2026 deals with glioblastoma, where a pump protein can push drugs out of cancer cells. The pigment comes from maqui, a Chilean berry rich in plant compounds that calm swelling.
The team worked with two cell lines and a mouse model. The test pigment cut output of a swelling signal and lowered the pump protein at both gene and protein levels. Paired with standard cancer drugs that the pump acts on, it made the cells more open to treatment. Tests used gene, protein, and light based reporter methods to track each step.
Catalog record
| CREATOR | Constanza Cuevas, Yessica Nahuelpan, Darling Haro, Pamela Silva, Vicente Villagran, María A. Gleisner, Flavio Salazar-Onfray, Juan P. Muñoz, Christian Pávez, Noemi Garcia-Romero, Angel Ayuso-Sacido, Rody San Martin, Diego Carrillo-Beltrán, Claudia Quezada-Monrás |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |