From Simulation to Therapy: Light Guidance Through Zirconium Dental Implants for Bone-Targeted Photodynamic Inactivation
Kolja Lehmann, Gabor Kadler, Heinrich Walt, Barbara Solenthaler, Harald Essig, Michael Guthe · 2026
Read From Simulation to Therapy: Light Guidance Through Zirconium Dental Implants for Bone-Targeted Photodynamic Inactivation by Kolja Lehmann, Gabor Kadler, Heinrich Walt, Barbara Solenthaler, Harald Essig, Michael Guthe (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13510031.txt.
Description
Lehmann and colleagues published a 2026 study on dental implants that pipe light into jawbone. Bacteria films on implant edges can trigger bone-losing gum disease there. Light-activated killing, called photodynamic inactivation, offers a gentler add-on treatment. Ceramic zirconia implants can themselves carry the light to the bone edge.
Computer simulations, built from CT scans, tracked the light spread in jawbone. Light passed the implant edge at strengths above the killing threshold set. Changing implant shape and light placement steered where the dose landed. Pig and human jaw tissue behaved alike in the optical measures. The path toward patient trials looks open, the authors conclude. Design tweaks could target uneven film patches case by case. The implant itself acts as the light guide in the concept.
Catalog record
| CREATOR | Kolja Lehmann, Gabor Kadler, Heinrich Walt, Barbara Solenthaler, Harald Essig, Michael Guthe |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |