Exploring the Impact of miR-10a, miR-141, miR-200a and miR-3658 on Cystinuria

Daniel Cernach Ayres, Ruan Pimenta, Gabriel Arantes dos Santos, Patrícia Candido, Milena Antunes, Nelson Gaspar Dip Junior, Giovanni S. Marchini, Fábio C. Torricelli, Fábio C. Vicentini, Alexandre Danilovic, Carlos A. Batagello, Kátia R. M. Leite, William C. Nahas, Sabrina T. Reis, Eduardo Mazzucchi · 2026

Read Exploring the Impact of miR-10a, miR-141, miR-200a and miR-3658 on Cystinuria by Daniel Cernach Ayres, Ruan Pimenta, Gabriel Arantes dos Santos, Patrícia Candido, Milena Antunes, Nelson Gaspar Dip Junior, Giovanni S. Marchini, Fábio C. Torricelli, Fábio C. Vicentini, Alexandre Danilovic, Carlos A. Batagello, Kátia R. M. Leite, William C. Nahas, Sabrina T. Reis, Eduardo Mazzucchi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13509378.txt.

Description

Daniel Cernach Ayres leads a fifteen-author team studying small RNA molecules in blood as possible markers for cystinuria, in work published in 2026. Cystinuria is an inherited condition where cystine builds up and forms repeated kidney stones. The group compared sixteen patients with confirmed cystinuria against eleven healthy people with no stone history. They measured eight candidate molecules chosen for their links to genes already tied to the disease.

Four molecules came out lower in patients than in healthy controls. Higher levels of three of them went with a greater number of past stone operations, and higher levels of one also went with weaker kidney function. The authors suggest these molecules reflect how severe the disease is, rather than acting as a simple yes-or-no test, and they call for larger studies to confirm the pattern.

Catalog record

CREATORDaniel Cernach Ayres, Ruan Pimenta, Gabriel Arantes dos Santos, Patrícia Candido, Milena Antunes, Nelson Gaspar Dip Junior, Giovanni S. Marchini, Fábio C. Torricelli, Fábio C. Vicentini, Alexandre Danilovic, Carlos A. Batagello, Kátia R. M. Leite, William C. Nahas, Sabrina T. Reis, Eduardo Mazzucchi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13509378

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