CD-73 blocking black phosphorus nanosheets hitchhiked on erythrocytes via affinity difference of AS1411 aptamer for targeted photothermal-immunotherapy of lung cancer

Qiao Liu, Niu Liu, Zhiqi Lao, Jian Qin, Yuting Zhong, Kaiwei Hou, Yuetao Zhao · 2026

Read CD-73 blocking black phosphorus nanosheets hitchhiked on erythrocytes via affinity difference of AS1411 aptamer for targeted photothermal-immunotherapy of lung cancer by Qiao Liu, Niu Liu, Zhiqi Lao, Jian Qin, Yuting Zhong, Kaiwei Hou, Yuetao Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13507855.txt.

Description

A peer-reviewed research article from Europe PMC (2026). Metabolic checkpoint inhibition targeting adenosine signaling combined with photothermal therapy (PTT) can remodel the immunosuppressive tumor microenvironment and enhance antitumor immunity in lung cancer, but its efficacy is limited by tumor-targeted accumulation. Leveraging the differential binding affinity of AS1411 aptamer (Apt) for nucleolin and actin, we developed an erythrocytes-based nanodelivery system incorporating red blood cell (RBC), black phosphorus nanosheets (BPs), the CD73 inhibitor AMPCP, and Apt.

Catalog record

CREATORQiao Liu, Niu Liu, Zhiqi Lao, Jian Qin, Yuting Zhong, Kaiwei Hou, Yuetao Zhao
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13507855

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