Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe · 2026

Read Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy by Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13507584.txt.

Description

Shota Sato and eight co-authors propose a tiny hollow tube made of gel that can sit inside a blood vessel and release drugs there, in 2026 work. Fiber-shaped carriers used before carried a risk of blocking flow and harming tissue. Their tube is made of barium alginate gel, a seaweed-based material that holds a stable network in flowing blood. A catheter delivers the tubes one by one into place.

The team tested the carriers in lab models that mimic vessels and in the kidney arteries of rats. Tubes stayed fixed in place while blood kept passing through the open center. They also delivered a model drug into a small kidney artery as intended. The design points toward targeted treatment inside vessels without cutting off the flow those tissues need.

Catalog record

CREATORShota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37695
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13507584

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