An Exploratory Study of the Short‐Term Association of Resistance Training With Circulating Inflammatory Biomarkers, Plasma Brain‐Derived Neurotrophic Factor, and Cognitive Function in Healthy Midlife Adults
Yu Ziyan, Chen Deqin, Chen Fanyue · 2026
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Description
Yu and colleagues examined whether four weeks of resistance training shifts inflammation, a brain-growth factor, and thinking performance in midlife adults, in a 2026 study. Five hundred adults aged fifty to sixty-five trained three times weekly, with blood tests and executive-function tasks before the program and three days after the last session. There was no comparison group, so results are before-and-after associations.
Yu found two inflammatory markers fell while brain-derived neurotrophic factor, a protein supporting neuron health, rose. Working memory accuracy improved and reaction time quickened, and performance on a color-word interference task improved. Participants who completed nearly all sessions showed larger numerical changes, though attendance was not randomized, so that pattern is only descriptive. The authors present the program as a feasible exposure for studying body-brain links and call for controlled trials with follow-up to test durability.
Catalog record
| CREATOR | Yu Ziyan, Chen Deqin, Chen Fanyue |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |