SLC27A1 overexpression correlates with lactylation and poor colorectal cancer progression
Yu Qi, Shumin Deng, Jun Zhang, Kuansong Wang · 2026
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Description
Yu Qi and co-authors examine a fat transport gene in colorectal cancer in a 2026 study. The gene, SLC27A1, makes a protein that moves fatty acids into cells. It has been linked to several cancers, but its role in this bowel cancer was not yet clear, so the team combined database work with lab tests.
They find the gene is turned up in tumors and that high levels track with worse features and poorer survival. High levels also track with immune cells inside tumors and with several cancer pathways. In lab cells, turning the gene down slowed cell growth. The work ties the gene to a chemical mark on proteins and points to it as a possible marker.
Catalog record
| CREATOR | Yu Qi, Shumin Deng, Jun Zhang, Kuansong Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |