Event-free survival and recurrence patterns after curative resection for locally advanced head and neck squamous cell carcinoma: single-institution real-world outcomes prior to the introduction of perioperative immunotherapy
Takuma Makino, Yuto Naoi, Go Hasegawa, Takuto Yamasaki, Hiroki Noda, Shohei Fujimoto, Junya Matsumoto, Mizuo Ando · 2026
Read Event-free survival and recurrence patterns after curative resection for locally advanced head and neck squamous cell carcinoma: single-institution real-world outcomes prior to the introduction of perioperative immunotherapy by Takuma Makino, Yuto Naoi, Go Hasegawa, Takuto Yamasaki, Hiroki Noda, Shohei Fujimoto, Junya Matsumoto, Mizuo Ando (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13506631.txt.
Description
Takuma Makino and colleagues present 2026 real-world outcomes for surgery in advanced head and neck cancer, before immune drugs around surgery came into use. Their single-center review covers 233 patients who had curative surgery for locally advanced squamous cell cancer. The team tracked event-free survival, overall survival, and whether return disease could still be treated.
One-year event-free survival reached about two thirds of patients, while overall survival was near nine in ten. Disease returned in about one third of patients, and salvage surgery linked to better survival after return. Heavy node spread and invasion into veins or nerves marked worse outlooks. The data give a baseline for judging newer combined care.
Catalog record
| CREATOR | Takuma Makino, Yuto Naoi, Go Hasegawa, Takuto Yamasaki, Hiroki Noda, Shohei Fujimoto, Junya Matsumoto, Mizuo Ando |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43264 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |