Clinical experience with de-escalated chemotherapy for a subset of high-risk gestational trophoblastic neoplasia at a single institution
Kosuke Yoshida, Taito Yoshida, Mari Shirasaki, Yuko Yasui, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama · 2026
Read Clinical experience with de-escalated chemotherapy for a subset of high-risk gestational trophoblastic neoplasia at a single institution by Kosuke Yoshida, Taito Yoshida, Mari Shirasaki, Yuko Yasui, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13506626.txt.
Description
Kosuke Yoshida and colleagues report 2026 results on lighter chemotherapy for a narrow group of high-risk pregnancy-related tumors treated at Nagoya University Hospital. Records span 268 patients treated from 1991 to 2023, scored by both the world FIGO system and the Japanese system. Forty-nine patients fell in the high-risk range.
Seventeen patients with FIGO scores of 7 to 8 split by Japanese scoring into invasive mole and choriocarcinoma groups. All seven invasive mole patients got reduced treatment and reached full remission. The authors suggest careful scoring can spare some patients stronger multi-drug treatment that they may not need, though wider checks are still required.
Catalog record
| CREATOR | Kosuke Yoshida, Taito Yoshida, Mari Shirasaki, Yuko Yasui, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23182 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |