Metabolic control of cellular reprogramming: phospholipid remodeling tunes auxin signaling
Jiajun Wang, Dandan Hu · 2026
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Description
Wang and Hu explain new work on how plant cells regain the power to regrow, a process that starts when cut tissue forms a callus, a lump of unspecialized cells. Auxin, a plant hormone, drives callus growth on rich culture medium through a known chain of gene switches. Writing in 2026, Wang and Hu review findings from Chang and colleagues on a missing piece of that chain: the reshaping of membrane fats called phospholipids during the shift.
Profiling the fats in Arabidopsis root pieces found 256 fat molecules that changed after auxin treatment. Among phospholipids, most fell in amount, including phosphatidic acid, a hub molecule that feeds into all major membrane fats. The reviewed work shows this remodeling is required for callus to form and tunes how cells hear the auxin signal. Fat handling, in short, acts as a control dial for plant regeneration, with uses for crop tissue culture.
Catalog record
| CREATOR | Jiajun Wang, Dandan Hu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |