Precision Oncology via Radiotherapy‐Triggered Drug Delivery: Mechanisms, Molecular Engineering, and Clinical Translation
Jianv Jiang, Tanfeng Zhang, Junliang Dong, Wenjing Sun · 2026
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Description
Jianv Jiang and co-authors review radiotherapy-triggered drug delivery for precision oncology. Their paper aims to join the spatial aim of ionizing radiation with controlled drug release.
Use in patients is held back because many systems need doses above clinical levels. The authors sort systems into two families: structural break-up and molecular switching. Reduction and electron-driven paths, they argue, are more robust and tumor-focused than pathways based on reactive oxygen species. Gas therapy driven this way is treated as its own kind. The central block is a dose-response mismatch, and they propose a design plan to close it.
Catalog record
| CREATOR | Jianv Jiang, Tanfeng Zhang, Junliang Dong, Wenjing Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 102 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |