A Novel Therapeutic Approach: Phage and Alhagi maurorum Synergy Against Kidney and Bladder Infection Caused by Proteus mirabilis in BALB/c Mice
Sharareh Moghim, Samira Choopani, Bahram Nasr Esfahani, Jean-Paul Pirnay, Jeroen Wagemans, Rob Lavigne, Arezoo Mirzaei · 2026
Read A Novel Therapeutic Approach: Phage and Alhagi maurorum Synergy Against Kidney and Bladder Infection Caused by Proteus mirabilis in BALB/c Mice by Sharareh Moghim, Samira Choopani, Bahram Nasr Esfahani, Jean-Paul Pirnay, Jeroen Wagemans, Rob Lavigne, Arezoo Mirzaei (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13504360.txt.
Description
Sharareh Moghim and six co-authors combine bacteria-killing viruses with a plant extract against stubborn urinary infections in mice. The target germ builds biofilms on catheters and shrugs off many drugs. Catheterized mice received a two-virus cocktail, an extract of the camelthorn plant, or both, at varied doses and lengths. Bacteria were then counted in kidney and bladder tissue. The strongest recipe paired the viruses at a matched dose with a high extract dose over seven days.
That combination cut kidney bacteria about ten-million-fold and bladder bacteria about two-hundred-thousand-fold. Stretching treatment from three days to seven mattered greatly for the kidneys. Both dose and duration shaped success, the authors stress, so the recipe needs tuning before any human use. They present the pairing as a grounded alternative for biofilm infections.
Catalog record
| CREATOR | Sharareh Moghim, Samira Choopani, Bahram Nasr Esfahani, Jean-Paul Pirnay, Jeroen Wagemans, Rob Lavigne, Arezoo Mirzaei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |