The Development and validation of an RP-HPLC-FD method for the multi-residue analysis of antiparasitic macrocycliclactones in cattle edible tissues

Busra Aslan Akyol, Nurullah Guclu, Kubra Deliklitas, Oguzhan Korkut, Fazilet Sen Metin, Cengiz Gokbulut · 2026

Read The Development and validation of an RP-HPLC-FD method for the multi-residue analysis of antiparasitic macrocycliclactones in cattle edible tissues by Busra Aslan Akyol, Nurullah Guclu, Kubra Deliklitas, Oguzhan Korkut, Fazilet Sen Metin, Cengiz Gokbulut (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13503942.txt.

Description

Busra Aslan Akyol leads a team that built a single test for five worm drugs in cattle tissues, in a 2026 paper. The drugs, from the macrocyclic lactone family, kill parasites at tiny doses, but traces can linger in meat, liver, kidney, and fat. Food rules cap those traces.

Their method pulls the drugs out with a quick extraction mix, then reads them with a liquid separation tool and a glow detector. Recovery across tissues ranged from about 74 to 96 percent, with detection limits near one part per billion. Of 168 real samples, 18 held traces, and just one meat sample broke the legal cap. The test uses one gram of tissue and little solvent, which cuts cost and waste.

Catalog record

CREATORBusra Aslan Akyol, Nurullah Guclu, Kubra Deliklitas, Oguzhan Korkut, Fazilet Sen Metin, Cengiz Gokbulut
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46430
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13503942

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