Hydrogel microneedles loaded with engineered extracellular vesicles accelerate diabetic wound healing by promoting angiogenesis and modulating macrophage polarization
Shaoyihan Fang, Jingjie Min, Zhenzhen Chen, Shuangyan Li, Yulu Zhou, Jingwen An, Zhongyi Chen, Dewu Liu · 2026
Read Hydrogel microneedles loaded with engineered extracellular vesicles accelerate diabetic wound healing by promoting angiogenesis and modulating macrophage polarization by Shaoyihan Fang, Jingjie Min, Zhenzhen Chen, Shuangyan Li, Yulu Zhou, Jingwen An, Zhongyi Chen, Dewu Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13503132.txt.
Description
Oxidative stress, impaired angiogenesis, and persistent inflammation contribute to delayed diabetic wound healing. In this study, ALDH2-loaded liposomes were associated with extracellular vesicles derived from human amniotic mesenchymal stem cells to generate an ALDH2@Lipo/EV hybrid formulation, which possess pro-angiogenic, antioxidant, and anti-inflammatory properties that modulate mitochondrial homeostasis in cells within diabetic wounds.
Catalog record
| CREATOR | Shaoyihan Fang, Jingjie Min, Zhenzhen Chen, Shuangyan Li, Yulu Zhou, Jingwen An, Zhongyi Chen, Dewu Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |