Assessment of the Optic Nerve Sheath Diameter by Bedside Sonography and Its Correlation With the Glasgow Coma Score in the Outcome of Patients With Sepsis-Associated Encephalopathy
Kirtikar Ghorela, Raju Shakya, Mukul Garg, Shivani Kumawat · 2026
Read Assessment of the Optic Nerve Sheath Diameter by Bedside Sonography and Its Correlation With the Glasgow Coma Score in the Outcome of Patients With Sepsis-Associated Encephalopathy by Kirtikar Ghorela, Raju Shakya, Mukul Garg, Shivani Kumawat (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13502924.txt.
Description
Kirtikar Ghorela leads a four-author team with a 2026 study testing whether ultrasound of the eye can track brain dysfunction in sepsis. Sepsis-associated encephalopathy clouds the brain without direct infection, and the optic nerve sheath diameter, measurable at the bedside, is proposed as a stand-in for raised pressure inside the skull. Eighty intensive care patients were treated at Indraprastha Apollo Hospitals in New Delhi. Enrolled between May 2021 and October 2022, they had sheath measurements and Glasgow Coma Scale scores recorded at diagnosis, 24 and 72 hours, day five, and any deterioration.
The two measures did not move together: no significant correlation appeared at time points, and baseline diameter ignored illness severity scores and length of stay alike. Twelve patients, 15 percent, died within 28 days. Non-survivors did average a wider baseline sheath, 5.35 versus 5.20 millimetres, yet splitting patients at a 5.5 millimetre threshold erased the mortality difference. The authors label the signal exploratory.
Catalog record
| CREATOR | Kirtikar Ghorela, Raju Shakya, Mukul Garg, Shivani Kumawat |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |