Complete remission of Helicobacter pylori-negative gastric MALT lymphoma following eradication therapy
Hui Chen, Jingtong Tang, Lin Mo, Xi Wang, Guobin He · 2026
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Description
Chen and colleagues reported a woman in her late fifties whose stomach lymphoma cleared after bacteria-eradication drugs. Tests had shown no trace of the culprit bacterium. Their 2026 report concerns gastric MALT lymphoma, a slow lymph-system cancer normally driven by Helicobacter pylori. Guidelines differ on whether patients without the bacterium should try eradication first.
Biopsies confirmed lymphoma confined to the stomach lining, while breath and tissue tests for Helicobacter were negative, though one value sat near the cutoff. After discussion she received a fourteen-day, four-drug eradication regimen including an acid blocker and two antibiotics. Two months later she was symptom-free, scans were clean, and biopsies showed remission, maintained at six months. The authors suggest other helicobacter species, drug effects on tumor cells, or immune changes may explain the response. They argue a negative test alone should not rule out a trial.
Catalog record
| CREATOR | Hui Chen, Jingtong Tang, Lin Mo, Xi Wang, Guobin He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |