Psychometric properties of patient-reported outcome measures for health-related quality of life in multiple myeloma: a systematic review based on COSMIN guidelines
Lili Xie, Qiong Feng, Jiaxin Wang, Weiyi Qin, Yuhong Ding, Zhishui Wu · 2026
Read Psychometric properties of patient-reported outcome measures for health-related quality of life in multiple myeloma: a systematic review based on COSMIN guidelines by Lili Xie, Qiong Feng, Jiaxin Wang, Weiyi Qin, Yuhong Ding, Zhishui Wu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13501831.txt.
Description
Lili Xie leads a six-author team presenting a 2026 review of questionnaires that measure quality of life in multiple myeloma, judged by the COSMIN standards for measurement quality. Twenty-six studies covering fourteen patient-reported instruments qualified. The myeloma-specific module EORTC QLQ-MY20 was evaluated most often, followed by instruments such as MyPOS, HM-PRO, and FACT-MM. Evidence clustered on internal consistency, structural validity, and construct testing, while measurement error, criterion validity, and cross-cultural validity were rarely examined.
No instrument earned uniformly high-quality evidence across all the properties that matter. The EORTC QLQ-MY20 and MyPOS carried the broadest supportive evidence and look like the most defensible choices for myeloma-specific use. Even they lack strong content validity work and long-term measurement studies. The authors urge future research to involve patients in validating what the forms ask, and to test responsiveness when health changes.
Catalog record
| CREATOR | Lili Xie, Qiong Feng, Jiaxin Wang, Weiyi Qin, Yuhong Ding, Zhishui Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 89334 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |