Remnant cholesterol inflammation index may be a superior biomarker to C-reactive protein-triglyceride glucose index in predicting carotid atherosclerosis risk
Nimei Zeng, Ting Tian, Quan Zhou, Yuanli Li, Ruixin Zhou, Fangfei Xie, Renfang Han, Yi Wang, Yun Wang, Wei Ni, Jingyi Fan · 2026
Read Remnant cholesterol inflammation index may be a superior biomarker to C-reactive protein-triglyceride glucose index in predicting carotid atherosclerosis risk by Nimei Zeng, Ting Tian, Quan Zhou, Yuanli Li, Ruixin Zhou, Fangfei Xie, Renfang Han, Yi Wang, Yun Wang, Wei Ni, Jingyi Fan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13501761.txt.
Description
Nimei Zeng leads an eleven-author team reporting a 2026 comparison of two composite blood indices for predicting carotid artery plaque, an early sign of atherosclerosis. One index, CTI, combines C-reactive protein with the triglyceride-glucose measure; the other, RCII, combines remnant cholesterol with inflammation. The team ran both a case-control study of 2,888 age- and sex-matched pairs and a prospective cohort of 4,418 plaque-free participants followed for a median of 767 days.
Both indices tracked higher plaque risk in both designs: odds ratios of 1.45 for CTI and 1.95 for RCII in the case-control arm, with similar hazard ratios in the cohort. Added to a traditional risk model, RCII reached an area under the curve of 0.704, edging CTI at 0.681 on that metric, and reclassification statistics favoured RCII as well. The authors conclude the remnant cholesterol index may be the stronger early-warning marker, pending larger validation.
Catalog record
| CREATOR | Nimei Zeng, Ting Tian, Quan Zhou, Yuanli Li, Ruixin Zhou, Fangfei Xie, Renfang Han, Yi Wang, Yun Wang, Wei Ni, Jingyi Fan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38999 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |