Elevated serum high-density lipoprotein is positively associated with incident glaucoma among middle-aged and older adults: a national cohort in China
Zilin Chen, Hanming Lin, Xianqi Zheng, Xi Song, Haitong Feng, Hui Guo, Xiaoyi Yu · 2026
Read Elevated serum high-density lipoprotein is positively associated with incident glaucoma among middle-aged and older adults: a national cohort in China by Zilin Chen, Hanming Lin, Xianqi Zheng, Xi Song, Haitong Feng, Hui Guo, Xiaoyi Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13501712.txt.
Description
Zilin Chen leads a seven-author team reporting a 2026 cohort study that links higher HDL cholesterol, the so-called good cholesterol, with greater glaucoma risk in older Chinese adults. Data came from the China Health and Retirement Longitudinal Study. The analysis followed 7,510 people over 45 who had no glaucoma at the 2011 baseline, recording new self-reported cases through 2018. Cox models adjusted for demographic and clinical background, and spline analysis probed the shape of the relationship.
Over seven years, 224 participants, 2.98 percent, developed glaucoma. Each extra millimole per litre of HDL carried a hazard ratio of 1.57 for new disease after adjustment. People with low HDL, below 1.0 in the same units, had a lower risk than those with normal levels, with a hazard ratio of 0.63 on that comparison. Risk rose most steeply at the lower end of the HDL range, and the link strengthened further among participants with liver disease.
Catalog record
| CREATOR | Zilin Chen, Hanming Lin, Xianqi Zheng, Xi Song, Haitong Feng, Hui Guo, Xiaoyi Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28420 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |