Exploring offspring behaviour after prenatal COVID-19 vaccination in mice
Lilla Otrokocsi, Fruzsina Maácz, Pál Tod, Flóra Gölöncsér, Beáta Sperlágh · 2026
Read Exploring offspring behaviour after prenatal COVID-19 vaccination in mice by Lilla Otrokocsi, Fruzsina Maácz, Pál Tod, Flóra Gölöncsér, Beáta Sperlágh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13500820.txt.
Description
Lilla Otrokocsi leads a five-author team with a 2026 mouse study of whether vaccines given in pregnancy affect how the offspring act. Pregnant mice received the COVID-19 mRNA vaccine BNT162b2, a flu vaccine, or a control, and pups were tested at four and eight weeks of age. Blood and fetal brain tissue were checked for immune markers: cytokines, the P2X7 receptor, BDNF, and fat oxidation damage. A comparison group received poly(I:C), which mimics viral infection.
The COVID vaccine raised two maternal cytokines modestly without inflaming the fetal brain. Some mild, age- and sex-linked changes in how pups acted appeared, but no consistent autism-like pattern emerged at either age. The flu vaccine caused smaller, passing effects, while poly(I:C) triggered strong inflammation and lasting changes. The authors conclude that prenatal COVID vaccination showed no widespread harm to brain development in this model.
Catalog record
| CREATOR | Lilla Otrokocsi, Fruzsina Maácz, Pál Tod, Flóra Gölöncsér, Beáta Sperlágh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 75231 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |