Growth and Neurodevelopmental Outcomes of Children With Congenital Hypothyroidism Identified Through Dried Blood Spot Newborn Screening at a Tertiary Care Hospital in Pakistan
Bushra Rehman, Muzna Arif, Abida Akbar, Nadia Mazhar, Zahra Hoodbhoy, Fozia Memon, Muhammad Nasheet Sagri, Sumaiyah Zahid, Hafsa Majid, Farzana Faqiruddin, Salman Kirmani, Khadija Nuzhat Humayun · 2026
Read Growth and Neurodevelopmental Outcomes of Children With Congenital Hypothyroidism Identified Through Dried Blood Spot Newborn Screening at a Tertiary Care Hospital in Pakistan by Bushra Rehman, Muzna Arif, Abida Akbar, Nadia Mazhar, Zahra Hoodbhoy, Fozia Memon, Muhammad Nasheet Sagri, Sumaiyah Zahid, Hafsa Majid, Farzana Faqiruddin, Salman Kirmani, Khadija Nuzhat Humayun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13499624.txt.
Description
Bushra Rehman and eleven co-authors report outcomes for babies caught by newborn thyroid screening in Pakistan, in a 2026 study. Congenital hypothyroidism is the commonest congenital hormone disorder and a leading preventable cause of intellectual disability. Pakistan has no national screening program, though local incidence looks higher than the global average.
One Karachi hospital screened dried blood spots from 53,799 babies between 2019 and 2024. Forty cases were confirmed. Thirty-nine children were followed, most of them girls, nearly all of normal birth weight. Prolonged jaundice was the commonest early sign. By age three, growth measures sat within the normal range for nearly all. Of thirty-four children with developmental records, thirty-two developed normally. The single case of global delay was blamed on a separate suspected metabolic disorder. The authors argue for expanding screening nationwide.
Catalog record
| CREATOR | Bushra Rehman, Muzna Arif, Abida Akbar, Nadia Mazhar, Zahra Hoodbhoy, Fozia Memon, Muhammad Nasheet Sagri, Sumaiyah Zahid, Hafsa Majid, Farzana Faqiruddin, Salman Kirmani, Khadija Nuzhat Humayun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |