Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion

Giampiero I Baroncelli, Daniele Tessaris, Tommaso Aversa, Enrica Bertelli, Pasquale Comberiati, Domenico Corica, Natascia Di Iorgi, Maria Felicia Faienza, Danilo Fintini, Roberto Franceschi, Anna Grandone, Mila Ann Karapurackal, Silvia Longhi, Marco Pitea, Andrea Secco, Giuliana Trifirò, Graziamaria Ubertini, Flavia Urbano, Francesco Vierucci, Malgorzata Wasniewska, Stefano Mora, Luisa de Sanctis · 2026

Read Practical approach to the diagnosis, management, and treatment of pediatric patients with bone fragility: an expert opinion by Giampiero I Baroncelli, Daniele Tessaris, Tommaso Aversa, Enrica Bertelli, Pasquale Comberiati, Domenico Corica, Natascia Di Iorgi, Maria Felicia Faienza, Danilo Fintini, Roberto Franceschi, Anna Grandone, Mila Ann Karapurackal, Silvia Longhi, Marco Pitea, Andrea Secco, Giuliana Trifirò, Graziamaria Ubertini, Flavia Urbano, Francesco Vierucci, Malgorzata Wasniewska, Stefano Mora, Luisa de Sanctis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13498659.txt.

Description

Giampiero I Baroncelli leads a panel of Italian child bone specialists offering in 2026 practical guidance on fractures caused by fragile bones in children and teenagers. Many childhood breaks come from accidents, yet some signal weak bones from inherited or secondary disease, and recognition can be delayed. The panel met online between November 2024 and June 2025, combining clinical experience with a review of published work.

Their statements cover seven areas, from defining fragility fractures and childhood osteoporosis to causes, chances of natural recovery, and drug and non-drug care. Genetic testing holds a central place for inherited forms, since it can pin down the cause. Bisphosphonate drugs, which slow bone breakdown, remain the main treatment, while measures to build bone strength may help selected patients, and some damaged vertebrae can reshape as children grow.

Catalog record

CREATORGiampiero I Baroncelli, Daniele Tessaris, Tommaso Aversa, Enrica Bertelli, Pasquale Comberiati, Domenico Corica, Natascia Di Iorgi, Maria Felicia Faienza, Danilo Fintini, Roberto Franceschi, Anna Grandone, Mila Ann Karapurackal, Silvia Longhi, Marco Pitea, Andrea Secco, Giuliana Trifirò, Graziamaria Ubertini, Flavia Urbano, Francesco Vierucci, Malgorzata Wasniewska, Stefano Mora, Luisa de Sanctis
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE80044
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13498659

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