Chiral Twin-Electrodes for Amplifying the Faradaic Current of Enantiomers via Redox Cycling

Sorasak Klinyod, Zikkawas Pasom, Gerardo Salinas, Patrick Garrigue, Véronique Lapeyre, Stéphane Reculusa, Chularat Wattanakit, Alexander Kuhn · 2026

Read Chiral Twin-Electrodes for Amplifying the Faradaic Current of Enantiomers via Redox Cycling by Sorasak Klinyod, Zikkawas Pasom, Gerardo Salinas, Patrick Garrigue, Véronique Lapeyre, Stéphane Reculusa, Chularat Wattanakit, Alexander Kuhn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13495725.txt.

Description

Sorasak Klinyod and colleagues build, in a 2026 study, a pair of mirror-aware electrodes that amplify the signal of one handedness of a molecule. Many drugs come in left and right forms with very different effects, yet telling them apart sensitively is hard. The device faces two metal electrodes stamped with the same chiral pattern across a narrow channel, so a matching molecule bounces between them, reacting again and again.

Each round trip adds to the measured current, multiplying the signal more than tenfold for the favored form. Using DOPA, a Parkinson's drug, as the test case, the setup told the two forms apart with about nine tenths efficiency. The electrodes are porous platinum-iridium alloys imprinted with one DOPA form or the other. The authors see a route to cheap, sharp sensors for chiral drugs and chemicals.

Catalog record

CREATORSorasak Klinyod, Zikkawas Pasom, Gerardo Salinas, Patrick Garrigue, Véronique Lapeyre, Stéphane Reculusa, Chularat Wattanakit, Alexander Kuhn
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13495725

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