Inverse Association between the Omega-3 Index and Neutrophil–Lymphocyte Ratio: Pooled Results from Four Supplementation Trials
Michael I McBurney, Nathan L Tintle, Jason Westra, Mélanie Plourde, Michael Flock, David M Mutch, Charles B Stephensen, John W Newman, William S Harris · 2026
Read Inverse Association between the Omega-3 Index and Neutrophil–Lymphocyte Ratio: Pooled Results from Four Supplementation Trials by Michael I McBurney, Nathan L Tintle, Jason Westra, Mélanie Plourde, Michael Flock, David M Mutch, Charles B Stephensen, John W Newman, William S Harris (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13494177.txt.
Description
Michael I McBurney and colleagues pool data from four omega-3 trials in a 2026 analysis of blood markers in healthy adults. The Omega-3 Index gauges how much of two fish-oil fats, EPA and DHA, sit in red blood cell walls. Earlier observational work tied a higher index to a lower neutrophil-lymphocyte ratio, a simple inflammation marker drawn from a blood count, so the team tested whether supplements move both.
Pooling 436 people, they found the index rose on EPA plus DHA and fell slightly without them. The inflammation ratio dropped in the supplemented group and barely changed in controls, and bigger index gains went with bigger ratio falls. A second marker, red cell size spread, did not track with the index. The authors say trials in people with high inflammation markers are still needed to show whether these shifts change health outcomes.
Catalog record
| CREATOR | Michael I McBurney, Nathan L Tintle, Jason Westra, Mélanie Plourde, Michael Flock, David M Mutch, Charles B Stephensen, John W Newman, William S Harris |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32976 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |