Gut microbiota responses to isocaloric macronutrient modulation in tissue-specific insulin resistance: a secondary analysis of the PERSonalized glucose Optimization through Nutritional intervention (PERSON) randomized trial
Kelly M Jardon, Alexander Umanets, Koen Venema, Inez Trouwborst, Anouk Gijbels, Gabby B Hul, Els Siebelink, Lydia A Afman, Gijs H Goossens, Ellen E Blaak · 2026
Read Gut microbiota responses to isocaloric macronutrient modulation in tissue-specific insulin resistance: a secondary analysis of the PERSonalized glucose Optimization through Nutritional intervention (PERSON) randomized trial by Kelly M Jardon, Alexander Umanets, Koen Venema, Inez Trouwborst, Anouk Gijbels, Gabby B Hul, Els Siebelink, Lydia A Afman, Gijs H Goossens, Ellen E Blaak (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13494108.txt.
Description
Kelly Jardon and nine co-authors read gut microbe shifts in a diet trial for insulin resistance in a 2026 paper. Tailored diets had already lifted heart and metabolic health in the parent trial, which split people by whether muscle or liver resisted insulin most. Whether gut microbes carried part of that lift was open. This second read digs into stool and blood marks.
One hundred seventy nine adults followed one of two set diets for twelve weeks at matched calories: one rich in a kind fat, one lean with more protein and fiber. Stool gene reads mapped the microbe crowd; sugar tests mapped the body side. The fat rich diet shifted the whole crowd makeup and the short chain fat makers in the liver resistant group. Links to health gains are traced in the full read.
Catalog record
| CREATOR | Kelly M Jardon, Alexander Umanets, Koen Venema, Inez Trouwborst, Anouk Gijbels, Gabby B Hul, Els Siebelink, Lydia A Afman, Gijs H Goossens, Ellen E Blaak |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |