Endothelial progenitor cells are associated with improved vascular repair in experimental aortic dissection
Pengcheng Du, Guanglang Zhu, Zhiqing Zhao, Yudong Sun, Zaiping Jing, Jiaxuan Feng · 2026
Read Endothelial progenitor cells are associated with improved vascular repair in experimental aortic dissection by Pengcheng Du, Guanglang Zhu, Zhiqing Zhao, Yudong Sun, Zaiping Jing, Jiaxuan Feng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13493997.txt.
Description
Du and colleagues explore a cell therapy for aortic dissection, a life-threatening tear in the wall of the body's main artery. Surgery and stents fix the tear mechanically but do little to heal the wall itself. Their 2026 study first noted that human dissection tissue, especially near the tear, accumulates cells resembling endothelial progenitor cells, the circulating repair cells that help reline blood vessels. The team then transplanted such cells into mice with an experimental form of the disease.
The transplanted cells homed to the injured aorta rather than spreading evenly. Treated mice showed less widening of the vessel, a more completely restored inner lining, and better preserved wall structure under the microscope. The benefits appeared in the early phase after injury, which is when dissection patients are most vulnerable.
Catalog record
| CREATOR | Pengcheng Du, Guanglang Zhu, Zhiqing Zhao, Yudong Sun, Zaiping Jing, Jiaxuan Feng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |