Association between carbohydrate quality index and cardiovascular disease: Tehran Lipid and Glucose Study

Zahra Gaeini, Parvin Mirmiran, Fereidoun Azizi · 2026

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Description

Gaeini, Mirmiran, and Azizi ask whether eating better-quality carbohydrates protects the heart, using long-running health data from Tehran. Their 2026 analysis followed 2,648 adults who were free of cardiovascular disease at the start. Diets were scored with a quality index built from fibre intake, blood-sugar impact, whole grain share, and how much carbohydrate came as solid food rather than drinks. Diet was recorded once, with a detailed questionnaire, between 2006 and 2008.

Over a median follow-up of about a decade, 171 participants developed cardiovascular disease, including heart attacks, strokes, and cardiovascular deaths. Comparing the highest and lowest thirds of diet quality, the team found no statistically clear link with disease risk after adjusting for lifestyle and health factors. Two rebuilt versions of the index told the same story. The authors stress the result is inconclusive rather than proof of no effect, since cases were few and diet was measured only once.

Catalog record

CREATORZahra Gaeini, Parvin Mirmiran, Fereidoun Azizi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE59 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13493900

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