Humoral Response to COVID-19 Vaccines and Infection during Sibeprenlimab Treatment of IgA Nephropathy
Kieran McCafferty, Jonathan Barratt, Yusuke Suzuki, Adrian Liew, Dana V. Rizk, Bobby Chacko, Laura Kooienga, Richard Lafayette, Muh Geot Wong, Marcela F. Pasetti, Mallory C. Shriver, Kristin Follman, Courtney Moc Willeford, Manisha Sahay, Gerard Honig, Lee Andrews, Lauren E. Olinski, Mohit Mathur, D · 2026
Read Humoral Response to COVID-19 Vaccines and Infection during Sibeprenlimab Treatment of IgA Nephropathy by Kieran McCafferty, Jonathan Barratt, Yusuke Suzuki, Adrian Liew, Dana V. Rizk, Bobby Chacko, Laura Kooienga, Richard Lafayette, Muh Geot Wong, Marcela F. Pasetti, Mallory C. Shriver, Kristin Follman, Courtney Moc Willeford, Manisha Sahay, Gerard Honig, Lee Andrews, Lauren E. Olinski, Mohit Mathur, D (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13493030.txt.
Description
Kieran McCafferty and co-authors report vaccine response during a kidney drug trial in 2026. The drug sibeprenlimab treats a kidney disease by blocking a factor that drives harmful antibodies. The trial ran during the COVID pandemic, which raised a natural worry. Would the drug blunt vaccine or infection responses along with the bad antibodies?
Data from the trial show the drug cut the harmful kidney linked antibodies as hoped. At the same time, protective responses to COVID vaccines and infection stayed intact. That split is welcome news for patients who need both kidney control and virus defense. The sub study adds safety depth to the main trial.
Catalog record
| CREATOR | Kieran McCafferty, Jonathan Barratt, Yusuke Suzuki, Adrian Liew, Dana V. Rizk, Bobby Chacko, Laura Kooienga, Richard Lafayette, Muh Geot Wong, Marcela F. Pasetti, Mallory C. Shriver, Kristin Follman, Courtney Moc Willeford, Manisha Sahay, Gerard Honig, Lee Andrews, Lauren E. Olinski, Mohit Mathur, D |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |