Epidemiology and clinical course of PFAPA syndrome in the pediatric population-single center study

Natalia Gołuchowska, Agata Tomaszewska, Aldona Ząber, Agata Będzichowska, Agata Knapik, Aleksandra Kudiuk, Agnieszka Rustecka, Bolesław Kalicki · 2026

Read Epidemiology and clinical course of PFAPA syndrome in the pediatric population-single center study by Natalia Gołuchowska, Agata Tomaszewska, Aldona Ząber, Agata Będzichowska, Agata Knapik, Aleksandra Kudiuk, Agnieszka Rustecka, Bolesław Kalicki (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13492027.txt.

Description

Natalia Gołuchowska and seven colleagues detail in 2026 the largest Polish picture yet of PFAPA syndrome. The condition is the commonest autoinflammatory disorder of childhood, named for its periodic fever, mouth ulcers, sore throat, and swollen neck glands. Records and questionnaires covered forty-seven children with confirmed diagnoses at one center.

Most children were boys, and over ninety percent had their first fever before age five. Episodes lasted about five days and returned roughly every three weeks, usually with swollen neck glands and coated tonsils, while most children felt entirely well between attacks. Blood tests during flares showed brisk inflammation in the small group tested. A single steroid dose aborted nearly every episode, and tonsil surgery ended fevers in five of six children who had it. The authors hope wider recognition cuts needless antibiotic use.

Catalog record

CREATORNatalia Gołuchowska, Agata Tomaszewska, Aldona Ząber, Agata Będzichowska, Agata Knapik, Aleksandra Kudiuk, Agnieszka Rustecka, Bolesław Kalicki
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31585
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13492027

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