Effect of PEEP titration on the incidence of elevated driving pressure in laparoscopic bariatric surgery: a randomized superiority trial
Saullo Queiroz Silveira, Sérgio M. Pereira, Leopoldo Muniz da Silva, Rafael Souza Fava Nersessian, Helidea de Oliveira Lima, Desiree Stieven Machado, João Pedro Borghi Moreira, Fernando Nardy Bellicieri, Glenio B. Mizubuti, Joaquim Edson Vieira · 2026
Read Effect of PEEP titration on the incidence of elevated driving pressure in laparoscopic bariatric surgery: a randomized superiority trial by Saullo Queiroz Silveira, Sérgio M. Pereira, Leopoldo Muniz da Silva, Rafael Souza Fava Nersessian, Helidea de Oliveira Lima, Desiree Stieven Machado, João Pedro Borghi Moreira, Fernando Nardy Bellicieri, Glenio B. Mizubuti, Joaquim Edson Vieira (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13491605.txt.
Description
Saullo Queiroz Silveira leads a ten-author team reporting a 2026 randomized trial on ventilator settings during weight-loss surgery performed through small incisions. Patients with obesity face lung stress under anesthesia when air pressure is poorly set. The trial tested whether a lung recruitment maneuver plus pressure-guided adjustment of PEEP, the pressure kept in the lungs between breaths, would prevent high driving pressure.
Seventy-eight patients were split among three strategies combining recruitment, guided adjustment, or fixed pressure. During the gas-inflated phase of surgery, high driving pressure struck far fewer patients in the guided group before and after recruitment. Blood pressure measures and later lung complications did not differ between groups. Careful pressure titration improved breathing mechanics during surgery without proven benefit afterward.
Catalog record
| CREATOR | Saullo Queiroz Silveira, Sérgio M. Pereira, Leopoldo Muniz da Silva, Rafael Souza Fava Nersessian, Helidea de Oliveira Lima, Desiree Stieven Machado, João Pedro Borghi Moreira, Fernando Nardy Bellicieri, Glenio B. Mizubuti, Joaquim Edson Vieira |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60492 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |