Ultra-sensitive label-free bio-detection via dielectric-modulated GOSC-SOI-TFET

S. N. Vittal Kollapudi, Manish Kumar Singh · 2026

Read Ultra-sensitive label-free bio-detection via dielectric-modulated GOSC-SOI-TFET by S. N. Vittal Kollapudi, Manish Kumar Singh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13490578.txt.

Description

Kollapudi and Singh simulated a switch device-based sensor that detects targets by how they change the electrical behavior of a tiny cavity near the device's passage junction. Label-free sensors skip the dyes and tags of lab assays, promising bedside speed. Their 2026 design uses a gate overlapping the source channel on an insulated silicon platform, modeled with realistic imperfections like uneven probe placement and targets crowding each other.

Response depended strongly on where captured targets sit, peaking when they lodge right at the passage junction. For gelatin samples the device's current response reached a figure on the order of hundreds of millions relative to baseline in the model run. Charged and neutral targets both registered, through varied mixes of the modeled passage mechanisms. Kollapudi presents the asymmetric gate and cavity placement as the keys to the extreme response claimed.

Catalog record

CREATORS. N. Vittal Kollapudi, Manish Kumar Singh
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE127 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13490578

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