Progesterone receptor, prokineticin 1, LncRNA-H19, and miR-210 in molecular regulation of recurrent implantation failure
Rahim Rostami, Jamileh Jahanbakhsh, Shirin Salehi, Katayoon Asgari, Soudabeh Fallah · 2026
Read Progesterone receptor, prokineticin 1, LncRNA-H19, and miR-210 in molecular regulation of recurrent implantation failure by Rahim Rostami, Jamileh Jahanbakhsh, Shirin Salehi, Katayoon Asgari, Soudabeh Fallah (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13490531.txt.
Description
Rostami and team compared womb-lining tissue from fifty women with recurrent implanting failure against fifty women with successful pregnancies, tracking a the hormone signaling network. Repeated failure of embryos to implant frustrates fertility treatment, and the lining's readiness is hormonally choreographed. Their 2026 case-control study at a Tehran hospital measured five linked molecules, from the the hormone receptor to a regulatory long RNA, by quantitative PCR.
The receptor's B form and the vessel-growth signal PROK1 both ran clearly low in the failure group, in gene activity and protein alike. Receptor and PROK1's receptor correlated strongly and positively, suggesting they rise and fall together in healthy lining. The regulatory RNAs shifted as well, completing a disrupted network picture. Rostami argues the panel could become a diagnostic fingerprint for lining that will not receive an embryo.
Catalog record
| CREATOR | Rahim Rostami, Jamileh Jahanbakhsh, Shirin Salehi, Katayoon Asgari, Soudabeh Fallah |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |