Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome—Evidence From a Human Dietary Intervention Study
Nicolaj S Bischoff, Anna K Undas, Greet van Bemmel, Marcel van Herwijnen, Marcha Verheijen, Simone G Van Breda, Jacco J Briedé, Lana Drenth‐Brink, Marcella Peelen‐Buijs, Iris Elferink, Héloïse Proquin, Henk van Loveren, Ad A van Bodegraven, Dick T H M Sijm, Theo M de Kok · 2026
Read Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome—Evidence From a Human Dietary Intervention Study by Nicolaj S Bischoff, Anna K Undas, Greet van Bemmel, Marcel van Herwijnen, Marcha Verheijen, Simone G Van Breda, Jacco J Briedé, Lana Drenth‐Brink, Marcella Peelen‐Buijs, Iris Elferink, Héloïse Proquin, Henk van Loveren, Ad A van Bodegraven, Dick T H M Sijm, Theo M de Kok (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13487354.txt.
Description
Bischoff and a Dutch team ran in 2026 a feeding trial on E171, the food grade form of titanium dioxide, a white dye once used in sweets and sauces. Europe pulled it from food over fears it could harm genes, but proof in humans was thin. Thirty one adults ate a set daily dose for two weeks. Each person also had a plain phase for contrast. The team checked stool, blood, and gut samples from each phase.
Stool titanium shot up during the dosed phase, as most of the dye passed through. Blood tests hinted at more oxidative stress, the rust like cell strain from stray oxygen forms. Gene readouts from colon samples showed seventy three pathways switched on. Those paths tie to stress, cell fuel use, and colon cancer linked steps. The shifts back the case for care with the dye in food.
Catalog record
| CREATOR | Nicolaj S Bischoff, Anna K Undas, Greet van Bemmel, Marcel van Herwijnen, Marcha Verheijen, Simone G Van Breda, Jacco J Briedé, Lana Drenth‐Brink, Marcella Peelen‐Buijs, Iris Elferink, Héloïse Proquin, Henk van Loveren, Ad A van Bodegraven, Dick T H M Sijm, Theo M de Kok |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |