Estimated glucose disposal rate outperforms inflammation surrogate markers in predicting cardiometabolic multimorbidity among middle-aged and older adults
Cancan Cui, Xu Wang, Liqiang Wang, Kaiming Xue, Jinghui Cao, Lingyu Zhang, Siqi Yue, Shengtong Chen, Lin Liu, Yanxi Liu, Jianshi Du · 2026
Read Estimated glucose disposal rate outperforms inflammation surrogate markers in predicting cardiometabolic multimorbidity among middle-aged and older adults by Cancan Cui, Xu Wang, Liqiang Wang, Kaiming Xue, Jinghui Cao, Lingyu Zhang, Siqi Yue, Shengtong Chen, Lin Liu, Yanxi Liu, Jianshi Du (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13483815.txt.
Description
Cancan Cui and co-authors compare two simple health indices for forecasting combined metabolic and heart conditions in later life. Their 2026 prospective cohort follows 7,589 Chinese adults aged 45 and older from a national aging study over nine years. One index estimates how well the body handles glucose, while the other reflects inflammation through a common blood protein.
During follow-up, 2,263 participants developed cardiometabolic multimorbidity, meaning at least two of diabetes, heart disease, and stroke together. Low glucose-handling scores doubled the hazard compared with high scores after standard adjustments. Risk stayed elevated for low scorers whether inflammation ran low or high. Adding the glucose index to a basic prediction model improved accuracy more than the inflammation marker did. A cheap calculated score may outperform a fashionable blood test here.
Catalog record
| CREATOR | Cancan Cui, Xu Wang, Liqiang Wang, Kaiming Xue, Jinghui Cao, Lingyu Zhang, Siqi Yue, Shengtong Chen, Lin Liu, Yanxi Liu, Jianshi Du |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35981 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |