Time to viral load suppression with 8-week versus 12-week ravidasvir/sofosbuvir regimens among chronic hepatitis C patients in Malaysia: a non-inferiority, randomized clinical trial
Nor Asiah Muhamad, Nor Soleha Mohd Dali, Nur Hasnah Maamor, Izzah Athirah Rosli, Fatin Norhasny Leman, S Maria Awaluddin, Huan Keat Chan, Rozainanee Mohd Zin, Muhammad Radzi Abu Hassan · 2026
Read Time to viral load suppression with 8-week versus 12-week ravidasvir/sofosbuvir regimens among chronic hepatitis C patients in Malaysia: a non-inferiority, randomized clinical trial by Nor Asiah Muhamad, Nor Soleha Mohd Dali, Nur Hasnah Maamor, Izzah Athirah Rosli, Fatin Norhasny Leman, S Maria Awaluddin, Huan Keat Chan, Rozainanee Mohd Zin, Muhammad Radzi Abu Hassan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13483159.txt.
Description
Nor Asiah Muhamad and co-authors describe a 2026 trial analysis asking whether eight weeks of hepatitis C drugs clear the virus as fast as twelve. The Malaysian trial randomised 321 adults with chronic infection to shorter or standard courses of a two-drug pairing, and this study clocked days until virus levels fell below the detection line.
Median time to clearance landed at twenty-eight days in both arms. Adjusted models gave the short arm a modest edge in odds of clearing sooner, though the authors warn the study had limited power for that claim. High starting virus levels slowed clearance in everyone. A wrinkle appeared by virus type: the short course looked strong in one genotype, while the dominant local genotype needs more proof before programs shorten care across the board.
Catalog record
| CREATOR | Nor Asiah Muhamad, Nor Soleha Mohd Dali, Nur Hasnah Maamor, Izzah Athirah Rosli, Fatin Norhasny Leman, S Maria Awaluddin, Huan Keat Chan, Rozainanee Mohd Zin, Muhammad Radzi Abu Hassan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43560 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |