Elevated Plasma T-LAK cell-originated protein kinase Owned the Potential for Predicting Favorable Outcomes in Acute Ischemic Stroke Patients

Lingzhi Li, Ziping Han, Tong Shen, Zhenhong Yang, Junfen Fan, Rongliang Wang, Yangmin Zheng, Haiping Zhao, Qingfeng Ma, Yumin Luo · 2026

Read Elevated Plasma T-LAK cell-originated protein kinase Owned the Potential for Predicting Favorable Outcomes in Acute Ischemic Stroke Patients by Lingzhi Li, Ziping Han, Tong Shen, Zhenhong Yang, Junfen Fan, Rongliang Wang, Yangmin Zheng, Haiping Zhao, Qingfeng Ma, Yumin Luo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13481614.txt.

Description

Lingzhi Li and co-authors present a 2026 study of a blood protein as a sign of strong recovery after a brain stroke. The protein, called TOPK, is best known from cancer work, and its role after stroke was open. The team measured TOPK in blood and in white cells of 330 patients with artery-block stroke and tracked function at three months.

Patients who reached top-level recovery carried clearly higher blood TOPK levels. Levels at or above a set threshold predicted top recovery on their own, and adding TOPK to standard clinical predictors sharpened their sorting power. The same held for patients who got clot-busting treatment. White cell gene levels for TOPK rose after stroke yet carried no prediction worth. A cheap blood check may help teams spot likely strong recoverers early.

Catalog record

CREATORLingzhi Li, Ziping Han, Tong Shen, Zhenhong Yang, Junfen Fan, Rongliang Wang, Yangmin Zheng, Haiping Zhao, Qingfeng Ma, Yumin Luo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42330
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13481614

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