Off-Label 16-mm VSD Occluder for Closure of a Giant PDA With Severe Pulmonary Hypertension
Sachin Sapkota, Purnima Sharma, Kahtan Fadah, Edgar Ivan Usle Perez, Vaishnavi Sabesan, Vishakh Prakash, Jyothsna Goranti, Sandesh Murali, Chalam Mulukutla · 2026
Read Off-Label 16-mm VSD Occluder for Closure of a Giant PDA With Severe Pulmonary Hypertension by Sachin Sapkota, Purnima Sharma, Kahtan Fadah, Edgar Ivan Usle Perez, Vaishnavi Sabesan, Vishakh Prakash, Jyothsna Goranti, Sandesh Murali, Chalam Mulukutla (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13480234.txt.
Description
Sachin Sapkota and colleagues present a 2026 case of closing a giant duct in the heart with a device built for a different hole. A 17-year-old girl had fainting spells, chest pain, and a constant heart murmur. Scans found a duct, a vessel that should shut after birth, measuring well over a centimetre wide, with lung pressures raised.
Months of lung vessel relaxing drugs eased resistance in the lung circuit, though values stayed borderline. The team then sealed the duct with a 16-millimetre plug designed for holes between the lower heart chambers. Her symptoms cleared, and the left heart chamber shrank back toward normal. The authors stress trial closure tests and joint review by heart and lung pressure specialists for borderline cases, rather than a single pressure number.
Catalog record
| CREATOR | Sachin Sapkota, Purnima Sharma, Kahtan Fadah, Edgar Ivan Usle Perez, Vaishnavi Sabesan, Vishakh Prakash, Jyothsna Goranti, Sandesh Murali, Chalam Mulukutla |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19608 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |